Cancer Research Focuses on Growing Tumor Cells Outside the Human Body

(NewsUSA) – One of the great barriers to improving the fight against cancer has been the problem of growing human cancer cells for drug testing so they behave as if they were inside the patient.To answer this, pharmaceutical companies are beginning to grow human tumors in mice. But mice are not human, so the tests often lead to dead ends. And while it’s possible to grow tumor cells in petri dishes, they rarely behave like actual cancers.But now this problem is being solved by a company called Precision Therapeutics Inc (NASDAQ:AIPT), formerly Skyline Medical Inc (NASDAQ:SKLN), and its partner, Helomics.Precision Therapeutics and Helomics, through a subsidiary named TumorGenesis, are pioneering an approach that takes cancer cells from a patient, then analyzes the tumors’ genes and proteins. That information is crucial because it guides the selection of nutrients and other substances that the cells need. The final step is putting the cancer cells not in a petri dish, but rather on a special scaffold that’s bathed in the nutrient-rich media.The result: "For the first time, it will be possible to grow tumors outside the body that closely mimic those in the body," explains Dr. Carl Schwartz, CEO of Precision Therapeutics.That, in turn, will bring major benefits for cancer treatment and drug discovery. Cancer is actually many thousands of different diseases, each with different underlying DNA mutations.That’s why drugs that are effective against one person’s ovarian cancer may fail utterly against another’s. But with the ability to grow the cancer cells from patients outside the body, doctors will be able to test drug combinations to discover what works before treating the patient, thus saving people from debilitating side effects from ineffective drugs.Equally important, pharmaceutical companies will have a far better and lower-cost way to test drug candidates than testing on mice. It’s yet another key step towards personalized cancer treatment that will give every patient a much better chance of long-term survival.

Virtual Colonoscopy Is Becoming a Reality for More People

(NewsUSA) – Colorectal cancer deaths are slowly declining, but shocking racial and ethnic disparities remain.According to the American Cancer Society, Latinos living in the United States are more likely to develop and die from this disease than those in many Central and South American countries. African-Americans are at least 41 percent more likely to die from colorectal cancer than whites.Both groups are also less likely to get screened, and their cancers are often found later.What can be done?A growing number of medical groups, patient advocates and members of Congress say virtual colonoscopy – known medically as CT colonography – can overcome cultural stigmas and anxiety associated with this screening."CT colonography can attract those who would otherwise not be screened, allow doctors to remove more polyps before they become cancers and help people avoid getting this disease," says Carolyn R. ("Bo") Aldigé, president and founder of the Prevent Cancer Foundation.The evidence is thereVirtual colonoscopy is an American Cancer Society-recommended screening exam. Studies show that it is as accurate as standard colonoscopy in most people – including those 65 and older.Virtual colonoscopy increases screening rates where it is offered in the U.S. and abroad. Former President Obama chose to have the virtual exam.Michael Sapienza, President and CEO of the Colon Cancer Alliance, says the virtual exam can "jump-start screening by offering access to a less-invasive option that millions of screening age who choose not to be tested find more appealing."Unfortunately, the prep is the sameHowever, the virtual exam is far less invasive than standard colonoscopy. The CT scanner uses low-dose X-rays to make 3-D, moving images of the colon that doctors examine for polyps and cancer.The test does not require sedation. It is over in minutes. And you may not need someone to drive you to the exam. Afterward, you can go back to daily activities.Private insurers are starting to listenThirty-six states require that insurance policies sold in their state cover virtual colonoscopy. Insurers who take part in federal exchanges are required under the Affordable Care Act to cover the exam. CIGNA, UnitedHealthcare, Anthem Blue Cross Blue Shield, Aetna and other insurers cover these tests irrespective of ACA requirements.Challenges remain for Medicare patientsScreening those on Medicare with virtual colonoscopy may cost nearly a third less than standard colonoscopy. Yet, Medicare is among a shrinking number of insurers that does not cover the test."We need more Medicare-covered options, including CT colonography, to increase Hispanic screening rates and save lives," says Elena V. Rios, MD, MSPH, president and chief executive officer of the National Hispanic Medical Association.Patient and provider groups want Congress to pass a new bill that would provide Medicare coverage for virtual colonoscopy."With Medicare coverage, CT colonography can increase screening and reduce unnecessary deaths," says Judy Yee, MD, chair of the American College of Radiology Colon Cancer Committee.Find more information on virtual colonoscopy (CT colonography) at

Teeth Grinding Can Be A Real Headache

(NewsUSA) – Did you know that if you suffer from nagging headaches – including migraines, tension headaches and behind-the-eye pain – your teeth could be the root of your problem?Involuntary and excessive clenching and grinding of the teeth (known in medical terms as bruxism) is a common condition, so prevalent that it affects 1 in 5 adults in the U.SAnd this number continues to increase.It’s probably no surprise to learn that bruxism can result in significant tooth wear and enamel erosion, leading to tooth surface sensitivity, chipped and fractured teeth, as well as a host of other dental issues that may require expensive treatment. But, what you may not realize is that over 90 percent of bruxism sufferers also experience headache pain caused by their teeth grinding.If you think about it, the link between teeth and jaw clenching, and headaches caused by teeth grinding, make a lot of sense. Because the jaw is capable of exerting more than 250 pounds of force when clenching, this amount of force can crack a walnut.This extreme tooth-on-tooth force helps explain tooth wear caused by teeth grinding and may also lead to temporomandibular joint (TMJ) pain and potential TMJ issues from teeth grinding.The temporomandibular joints are flexible joints found on each side of your head in front of the ear. Responsible for all jaw movements including eating and talking, they are the most active joints in your body and thus endure a lot of wear and tear. They connect the lower jaw to the temporal bone of the skull. Excessive teeth clenching and grinding, which generally occurs during sleep, puts pressure on these joints and as a result can cause far-reaching pain in your temples, behind the eyes, in the back of your neck and through your cheeks and ears.The exact cause of bruxism is not known, but it is widely believed that stress is a primary trigger and once the stressful event has passed, the clenching and grinding usually subsides. However, the amount of damage and tooth wear caused by teeth grinding that can be done within a brief period can be significant.That is why it so important that you seek treatment once you realize you are a teeth grinder, not only to stop your nagging headache pain, but also to prevent any further damage to your teeth.While there is no medication currently available to treat bruxism, dental experts recommend wearing a dental grind guard to protect the teeth from further damage and potentially help alleviate TMJ pain.To this end, Ora-GUARD is a dental grind guard unlike any other. Ora-GUARD’s revolutionary, patented design combines a soft, medical-grade material for fitting and cushioning the teeth during clenching, combined with a hard surface design that allows your teeth and jaws to slide naturally forward, protecting your teeth from the damaging effects of grinding and at the same time releasing tension in the TMJ muscle.For those looking for headache and pain relief from teeth grinding and TMJ, Ora-GUARD could be the answer.Visit for more information. 

Investigational Therapy May Change How Urinary Tract Cancer is Treated

(NewsUSA) – An investigational drug for a rare cancer of the upper urinary tract is currently being studied in over 25 centers across the United States.The cancer is called upper tract urothelial carcinoma (UTUC). It affects the lining of the kidney and the ureter, the tube that connects the kidney to the bladder.UTUC can be classified as high-grade or low-grade. People diagnosed with the high-grade disease usually must have their kidney, or both their kidney and ureter, removed. Those with low-grade UTUC can sometimes be treated by tumor removal using a special scope.Unfortunately, the procedure to remove the tumor is associated with a high rate of recurrence, and repeated procedures are often required. Around 20 percent of patients with low-grade UTUC eventually require kidney and ureter removal due to disease recurrence or progression.There are about 7,500 new cases of UTUC diagnosed in the United States annually. To date, no drugs have been approved by the U.S. Food and Drug Administration for the treatment of UTUC.The challenge of treating UTUC is rooted in the way the body functions. Urothelial cell cancers in the bladder are treated by surgical removal followed by chemotherapy instilled in the bladder and applied directly to the cancer cells. This approach is extremely challenging in the kidney and ureter because the flow of urine rapidly washes the medication away before it has time to work."It is exciting to have a clinical trial underway to study an investigational drug that may allow chemotherapy drugs to remain in the upper tract for a prolonged time," notes Diane Zipursky Quale, Co-Founder of the Bladder Cancer Advocacy Network.Well-designed clinical trials are the best way to determine whether an investigational drug is safe and effective and offers an acceptable balance of risks and benefits."The OLYMPUS study may shift how low-grade UTUC is treated in the future," says Karim Chamie, MD, MSHS, Associate Professor of Urology at UCLA. "As a urologist, I am excited about the possibility of providing an alternative to surgery for my patients diagnosed with low-grade UTUC."If you are interested in learning more about clinical trials for investigational treatments of low-grade UTUC, such as the OLYMPUS trial, speak to your doctor about the possibility of participating in a clinical trial.You can also visit or go to (NCT02793128) to find a clinical trial site in your area.

New Non-Prescription Medical Food Offers Help For Meal-Triggered Indigestion

(NewsUSA) – Recurring indigestion that is frequently triggered by a meal is a problem without a solution for many people. The medical condition, known as Functional Dyspepsia, has no known organic cause. No FDA-approved prescription products are currently available for meal-triggered indigestion or Functional Dyspepsia, so sufferers often turn to off-label products, including proton pump inhibitors (omeprazole and esomeprazole), antacids, and antidepressants, among others, to ease symptoms.The most common symptoms of meal-triggered indigestion or Functional Dyspepsia are nausea, bloating, belching, inability to finish a normal-size meal, feelings of fullness and pressure in the upper belly and upper-belly pain or burning.But sufferers may find help with FDgard, a new non-prescription medical food specially formulated for the dietary management of meal-triggered indigestion or Functional Dyspepsia, which affects an estimated 1 in 6 adults in the U.S.FDgard is the only non-prescription medical food clinically studied for this relatively common but frustrating condition, and it’s available in local pharmacies nationwide. Each FDgard capsule contains targeted-release microspheres of caraway oil and l-Menthol, the primary component found in peppermint oil, engineered for release in the upper belly, where discomfort most often occurs. The combination of caraway oil and l-Menthol have demonstrated effectiveness in reducing or improving dyspepsia discomfort, including feelings of pain and burning, early fullness, pressure, and bloating, which makes FDgard an ideal pre-meal companion to help control meal-triggered symptoms.Based on results of two peer-reviewed and presented studies at the American College of Gastroenterology meeting in October 2017, FDgard showed a high level of patient satisfaction and rapid improvement of Functional Dyspepsia symptoms. In a first-ever clinical study conducted in eight centers across the U.S., known as FDREST (Functional Dyspepsia Reduction and Evaluation Safety Trial), FDgard showed significant reduction and rapid relief of Functional Dyspepsia symptoms in 24 hours. In a second real-world, patient-reported outcomes study of 600 patients, called FDACT (Functional Dyspepsia Adherence and Compliance Trial), the findings showed a high level of patient satisfaction and overall symptom relief with FDgard.More and more doctors are turning to FDgard for the management of meal-triggered indigestion or Functional Dyspepsia. In fact, in a recent nationwide survey of 200 gastroenterologists, FDgard was the number-one-recommended herbal product for Functional Dyspepsia."Functional Dyspepsia can have a significant impact on one’s quality of life," says Michael Epstein, M.D., F.A.C.G., A.G.A.F., a leading gastroenterologist and Chief Medical Advisor of IM HealthScience, LLC."People are afraid to eat, they are afraid to go out to restaurants, they are afraid to sit down and enjoy a meal with friends," he says. "I explain to my patients that what we are dealing with is not a life-threatening medical condition."Dr. Epstein says that in his experience, FDgard is a great addition for fast relief of frustrating Functional Dyspepsia symptoms, especially since some patients want to take a natural product with minimal side effects. "I appreciate having this effective, non-prescription option for my patients, so more patients can proactively manage their Functional Dyspepsia symptoms."He explains that the combination of l-Menthol and caraway oil works synergistically to address the pain, pressure and early fullness that people with meal-triggered indigestion or Functional Dyspepsia experience.FDgard should be taken under a doctor’s supervision; the usual adult dosage is two capsules twice daily. FDgard is available in the digestive aisle at Walgreens, CVS and Rite Aid nationwide.Learn more by visiting

How Chiropractic Care Can Help Fight Presenteeism At Work

Even with a stronger economy, businesses face an uphill battle when it comes to making a profit. Which is why it’s not surprising that much of a company’s success hinges on its employees. But what if an employee is fighting a medical condition or illness? How impactful is that to a business’s bottom line? It turns out: quite a lot.

Unlike absenteeism, according to a recent study, presenteeism – when people show up for work but don’t or can’t perform at full capacity – isn’t always apparent. You know when someone doesn’t show up for work, but you often can’t tell when – or how much – health problems, including chronic conditions such as back pain, headaches, and arthritis, can leave them muddling through the day.

Three Ways Older Americans Can Benefit From Chiropractic Care

As a nation, America is getting older. So too is its population, with 10,000 Baby Boomers turning 65 every day. And even if you don’t want to admit it, you are most likely experiencing the same nagging aches and pains that you thought only plagued your parents.

Assuming you’re one of the nation’s 100 million chronic pain sufferers, in all likelihood you’re looking for a safer alternative for treatment other than opioids – especially with headlines of people becoming addicted to prescription painkillers and even dying from them. To see if drug-free chiropractic care is for you, read on.

At-Home Infusion Gives Gift of Health to Patients

(NewsUSA) – Hemophilia, a blood disorder in which the blood fails to clot properly, is a rare condition, but for those who have it, staying healthy can be challenging.The treatment for hemophilia is multifaceted, but it can include preventive care at home. Patients can give themselves infusions of clotting factors that are normally present in the blood to help prevent excessive bleeding episodes, which can be life-threatening and cause permanent damage.Repeated self-infusion as a preventive measure is associated with a lower incidence of the joint problems that can arise from excessive bleeding.In a recent study, 60 adult blood-disorder patients who self-infused experienced fewer joint problems by preventing the levels of clotting factors in the blood from falling below 1 percent of what is considered normal. Joint problems can become debilitating if left untreated, and patients may be unable to perform routine daily activities, attend school or work, or walk without a cane, walker, or other assistance.In addition, blood-disorder patients who self-infuse have reported feeling more confident and in- dependent, and appreciate the convenience of infusing at home, according to data from NCHS, a specialty pharmacy service for blood-disorder patients.Most importantly, the opportunity to infuse at home also may serve to motivate patients to take their medications as directed."Working to improve non-adherence among patients who intentionally stop their medications or intentionally disregard their prescribers’ instructions can be more of a challenge than simply helping patients remember to take their meds," according to a report from NCHS. "But if you understand why patients are making these choices, you may have better results."Common reasons why patients with a chronic disease such as a blood disorder fail to take their medications as directed include:* Concerns about the high cost of the medication.* Concerns about the medication’s side effects and whether it’s necessary.* Complexity of the treatment.* Communication issues with doctors about the value and benefits of the medication.Service providers like NCHS can help patients achieve more independence by offering discreet home delivery of medications, education and support. Services include detailed explanations about the use, dosing, storage, and side effects of medications so patients feel confident in their at-home care, as well as reimbursement expertise and caregiver education and counseling.For more information about NCHS and managing blood disorders, visit

Can Chiropractic Care Help Fight Presenteeism At Work?

(NewsUSA) – There’s a name for what may be ailing some businesses and their employees: presenteeism.That’s when people show up for work but don’t perform at full capacity, and – for one big reason – definitely not to be confused with those who routinely waste time at their desks, say, watching the latest cat video to go viral.That reason? Underlying health problems – including chronic conditions like back pain, headaches, and arthritis – that leave them muddling through the day."Underlying the research on presenteeism is the assumption that employees do not take their jobs lightly, that most of them need and want to continue working if they can," the Harvard Business Review reported.Many say the problem has only been exacerbated by the current opioid crisis, and that it’s in employers’ interests to see that their workers have access to safer options to such potentially addictive (or worse) prescription painkillers like OxyContin. One popular approach for relief from neuro-musculoskeletal issues like low-back and neck pain – drug-free chiropractic care – has actually been incorporated in on-site wellness programs by companies like Google, Apple and Facebook.Doctors of chiropractic, who are highly educated and trained in the structure and function of the human body, use hands-on techniques designed to enhance flexibility, muscle strength, and range of motion. Most insurance policies cover its use."Chiropractic care is a win-win situation for both businesses and their employees," said the Foundation for Chiropractic Progress’ Sherry McAllister, DC.So how much money does presenteeism cost businesses? According to a new report by Global Corporate Challenge, 10 times as much as the $150 billion annually in productivity lost from absenteeism.For more info, visit

Pain Sufferers May Not Find The Relief

Perhaps it’s because of the horrific news of opioid abuse recently, but it seems as if Americans are more seriously considering whether or not to take any kind of prescription medicine to relieve pain, according to a new study.

In fact, 78 percent of those surveyed in a joint effort by Gallup and Palmer College of Chiropractic said they’d “prefer to try other ways to address their physical pain before they take pain medication.”